997 research outputs found

    Proceedings of the 5th QS-APPLE Conference

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    This volume is a post-conference publication containing the refereed papers and abstracts of all presentations at the QS-APPLE Conference held in Kuala Lumpur, Malaysia from 24th-26th November, 2009

    The response of the Free Church of Scotland to the First World War, 1914-1919

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    The role of religion, and of Christianity in particular, in the context of a doctrinally conservative denomination engaging with theological issues arising from war should be investigated, with the Free Church of Scotland as a benchmark for such a study. That a study of the Free Church of Scotland - a small Presbyterian denomination - in relation to a war defined as “Great” should be undertaken presupposes the importance of religion as a contributing factor in understanding the conflict from small as well as large religious institutions. Thus, the theological and moral aspects of the War relating to divine causation of war, the nature of salvation in the context of death in battle, eschatological interpretation of the War and spiritual comfort and revivification as a result of warfare should be analysed through the spectrum of a denomination facing up to the challenges that war presented in these areas, challenges that the Free Church sought to meet with a robust determination to maintain its traditional confessional teaching

    Optimization of MicroGroove Copper Tube Coil Designs for Flammable Refrigerants

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    The ultralow Global Warming Potential (GWP) of propane (R290) and isobutane (R600a) refrigerants make them highly attractive for refrigerator and freezer applications, although their flammability necessitates strict use conditions with respect to refrigerant charge. Copper tubes with smaller diameters are widely used to reduce refrigerant charge. The process of downsizing copper-tube diameters involves detailed simulations and prototype construction as well as testing and validation. A proprietary heat exchanger design and simulation software tool (Jiang et al., 2006) was used to evaluate the performance of and optimize the design of domestic refrigerator condenser coils made with 5-mm outer-diameter copper tubes. Optimization was accomplished through the use of reduced order models, meta-models and a multi-objective genetic algorithm (MOGA). Reducing refrigerant charge was the primary objective. Secondary objectives included the reduction of the total footprint and the total tube-and-fin material mass. The baseline design used 6.35-mm O.D. copper tubes with a minimum wall thickness of 0.41 mm, i.e., quarter-inch tubes with 0.016-inch wall thickness. The new designs use wavy-herringbone fins with reduced fin thicknesses as compared to the baseline design. Other variables included the horizontal and vertical spacing of the tubes; number of tubes per bank; fin density; wavy fin pattern depth; tube length; and tube circuitry. For an R600a residential application, reduced internal volume was considered to be more important than the airside pressure drop. A Pareto chart is presented of optimized values from the design space. Compared to the baseline design, the best 5-mm design reduced the internal tube volume by 41 percent, along with a 57 percent reduction in coil footprint. Additionally, test data to validate the performance of prototype coils is presented with emphasis on the design, construction and manufacture of the heat exchanger coils

    Reframing ‘well-being’ in schools: the potential of recognition

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    In Australia and internationally, the well-being of children and young people is a core focus of social policy, with a growing imperative to locate well-being within the sphere of education. However, the term ‘well-being’ remains ambiguous and the implementation of educational approaches to promote and improve it appears fragmented and ad hoc. In Australia, little is known about how well-being is understood and supported in schools, particularly from the perspective of students themselves. This article reports on key findings from an ambitious mixed-methods study funded by the Australian Research Council that investigated conceptualisations and practices around well-being in schools. Underpinned by theoretical interests linked to Childhood Studies and recognition theory, the research investigated policy, student and staff perspectives on well-being. The findings point to the key role of relationships, providing considerable scope for analysing the salience of Honneth’s modes of recognition for well-being in schools

    The use of PCR-based methodologies to characterize salmonella serotypes of poultry origin

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    Three studies were conducted to investigate the use of molecular techniques to identify Salmonella serotypes in poultry. In the first experiment, two polymerase chain reaction (PCR)-based techniques: denaturing gradient gel electrophoresis (DGGE) and polyacrylamide gel electrophoresis (PAGE) were used to analyze Salmonella serotype isolates from two turkey processing plants (A and B). Genotypic patterns of each isolate were compared with those of known serotypes identified by traditional antibody precipitation methods. In Plant A, four different Salmonella serotypes were identified: Derby, Hadar, Montevideo, and Senftenberg. In plant B, ten serotypes were identified: Agona, Anatum, Brandenburg, Derby, Hadar, Meleagridis, Montevideo, Reading, Senftenberg, and Typhimurium. S. Derby was predominant in Plant A (83%) while S. Typhimurium was the most common serotype recovered in Plant B (39%). Overall, DGGE was more sensitive than PAGE. Isolates of the same serotypes were all grouped together by DGGE, while PAGE failed to group all like serotypes. Next, DGGE and REP-PCR were used as genotyping tools for identifying Salmonella. Fifty-four Salmonella isolates from two turkey processing plants (A and B) were evaluated. The isolates were comprised of the following serotypes: Brandenburg, Derby, Hadar, and Typhimurium (n = 6, 21, 12, and 15, respectively). Both methods were very sensitive and detected diverse fingerprint profiles among the isolates. The data suggested that REP-PCR and DGGE are useful tools for identifying Salmonella serotypes in research trials of this type. The final trial was carried out to track Salmonella serotypes throughout an integrated poultry operation using DGGE. Four flocks were sampled from grow-out through processing. The data showed that there was correlation between Salmonella serotypes found on processed carcasses and during grow-out. In addition, the isolates were compared against 15 known serotypes in our data base and only S. Hadar from the data base matched the unknown Salmonella isolates. Overall, these studies demonstrate that PCR-based methods could be considered as an alternative to conventional methods of antibody-based serotyping. Molecular methods were found to be reliable, sensitive, inexpensive, reproducible, and less labor intensive than conventional methods

    Testosterone Amplifies the Negative Valence of an Agonistic Gestural Display by Exploiting Receiver Perceptual Bias

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    Many animals communicate by performing elaborate displays that are incredibly extravagant and wildly bizarre. So, how do these displays evolve? One idea is that innate sensory biases arbitrarily favour the emergence of certain display traits over others, leading to the design of an unusual display. Here, we study how physiological factors associated with signal production influence this process, a topic that has received almost no attention. We focus on a tropical frog, whose males compete for access to females by performing an elaborate waving display. Our results show that sex hormones like testosterone regulate specific display gestures that exploit a highly conserved perceptual system, evolved originally to detect \u27dangerous\u27 stimuli in the environment. Accordingly, testosterone makes certain gestures likely to appear more perilous to rivals during combat. This suggests that hormone action can interact with effects of sensory bias to create an evolutionary optimum that guides how display exaggeration unfolds

    Acute high-intensity interval exercise-induced redox signaling is associated with enhanced insulin sensitivity in obese middle-aged men

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    Background: Obesity and aging are associated with increased oxidative stress, activation of stress and mitogen activated protein kinases (SAPK), and the development of insulin resistance and metabolic disease. In contrast, acute exercise also increases oxidative stress and SAPK signaling, yet is reported to enhance insulin sensitivity and reduce the risk of metabolic disease. This study explored this paradox by investigating the effect of a single session of high-intensity interval-exercise (HIIE) on redox status, muscle SAPK and insulin protein signaling in eleven middle-aged obese men. Methods: Participants completed a 2 h hyperinsulinaemic-euglycaemic clamp at rest, and 60 min after HIIE (4 × 4 mins at 95% HRpeak; 2 min recovery periods), separated by 1–3 weeks. Results: Irrespective of exercise-induced changes to redox status, insulin stimulation both at rest and after HIIE similarly increased plasma superoxide dismutase activity, plasma catalase activity, and skeletal muscle 4-HNE; and significantly decreased plasma TBARS and hydrogen peroxide. The SAPK signaling pathways of p38 MAPK, NF-ÎșB p65, and JNK, and the distal insulin signaling protein AS160Ser588, were activated with insulin stimulation at rest and to a greater extent with insulin stimulation after a prior bout of HIIE. Higher insulin sensitivity after HIIE was associated with higher insulin-stimulated SOD activity, JNK, p38 MAPK and NF-ÎșB phosphorylation (r = 0.63, r = 0.71, r = 0.72, r = 0.71; p < 0.05, respectively). Conclusion: These findings support a role for redox homeostasis and SAPK signaling in insulin-stimulated glucose uptake which may contribute to the enhancement of insulin sensitivity in obese men 3 h after HIIE

    Predictors of an early death in patients diagnosed with colon cancer : A retrospective case-control study in the UK

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    Acknowledgements The authors gratefully appreciate the contribution of data abstractors: Donna Floyd, Rosemary Ward, Jacqui Napier, Kate Donnelly and BrĂ­d Morris. The authors also thank Business Services Organisation, Health and Social Care NI for facilitating the note review. Finally, the authors would like to thank all patients whose data was used in this studyPeer reviewedPublisher PD

    Assessing Student Participation at School: Developing a Multidimensional Scale

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    In the past few years there has been a growing interest in student participation at school, and in whether participation is connected with student wellbeing or with academic success. One problem when studying student participation is that it seems to mean different things to different people. For some people it is just about students attending school and going to lessons. For others it is about students making decisions about things that matter to them, or being part of “student voice” activities at school. Another problem is that we do not have good ways to measure how well schools are doing at student participation, with tools that take account of the different ways that students can participate. This article reports how a new tool has been created to measure student participation. The new tool is called the Student Participation Scale. It was created in New South Wales (NSW), Australia. The researchers read books and articles on student participation. They also talked to school staff and students to find out what student participation meant to them, and they asked them about what questions should go into the tool. Once they created the Student Participation Scale, the researchers tested it on 1,435 secondary school students. The Scale asks 38 questions to measure six types or “elements” of student participation: Students working together with peers and school staff, Students having a voice about schooling, Students having a say with influential people at school, Students having influence on decisions made at school, Students having a voice about school activities outside of the classroom, and Students having choice. These elements of student participation were the same for boys and girls, for different grade or year groups, for students who spoke English as a second language, for students from an Indigenous background, and for students with a disability. The Scale was also consistent and valid. That is, it measured what the researchers said it would measure. The Student Participation Scale is easy and free for schools to use. It can be used to measure which elements of participation are happening most, and which ones schools might try to improve. There is also a guidebook that has instructions and tips for using the Scale in schools
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